Warning: This is a long review in which I share with like-minded consumers the research I did for myself on the science behind this product. If you are not a consumer who is interested in scientific research, you will probably prefer to skip to the very bottom of this review where I give my own testimony and/or move on to reviews which consist entirely of personal testimonials for this product.Now on to the review:Most of the medical research on the efficacy of systemic oral enzymes aka proteolytic enzymes (PE), such as are contained in this product, has been done outside the US, particularly in Europe. One of the chief, well documented functions of PE is to lower levels of inflammation throughout the body. Inflammation is implicated in virtually every known disease (see my review of "Walker Bait" I could not walk let alone run any distance because of heel pain.Jan 2012, I developed unbelievable heel pain in bottom right heel - like walking on something sharp. Thought it was bruised but pain got worse - not better- exquisite pain. After weeks of hell (and Alieve), I remembered Wobenzyme and found a 3 year old bottle. Old or not, I started taking 5 Wobenzyme a day X 4 times on an empty stomach (with a little water) - ANYTHING TO STOP THE PAIN. I could walk only a short distance even walking on the side of my foot didn't help. Grocery shopping, walking across a parking lot - everyday living - agony. I am definitely "walker bait".After 2 days of Wobenzye on an empty stomach and swallowing 4 tablespoons of coconut oil x 4 times a day with meals/snack which my friend swears cuts down inflammation, I got no relief from the pain. Yesterday, in desperation, I ordered a gel and regular heel insert ($50.00) from heel-that-pain website. I also ordered another 800 tablets Wobenzyme bottle on Amazon. Laugh if you must but in desperation, I stuck my right foot in an old pie tin with the bottom covered in coconut oil in an attempt to get the oil to absorb directly into the pain/inflammation. Stuck on the couch or behind my desk (at home), that is where my foot was.Day 3 Heel painful when stepping on it this morning but at least now if foot not moving, there was no throbbing. It still hurt to walk but I can at least walk short distances longer before the pain became too bad. Saw on the internet an exercise for heel. Put a short thin pipe under my desk chair and keep toes on the pipe while lifting the heel up and down stretching the foot/calf muscles. Hurts the heel so can only go so far.Day 4. My heel is definitely better. I can flex my foot which is something I could not do at all before and oddly enough as long as I wear sandals, slippers or running shoes on my home's hard tile floor, I can walk around with little to no pain. My heel hurts when I press the bottom of it with my finger but the CONSTANT PAIN is gone. I am so grateful!!!! Read another reviewer who said not to point toes down when lying down - something to do with muscles so I don't do that at least when I am awake. I continue taking the wob E 5 tablets x 4 times a day on empty stomach and taking the 4 tablespoons of coconut oil x 4 times a day and soaking my right foot in coconut oil.Day 5. The "old" Wobencyme tablets haven't killed me and my heel is definitely improving. A walk to mailbox only slightly painful. No long walks yet. Wished paid for a rush delivery on those heel inserts. I continued rotating my foot around and flexing it towards my head which is painful now only if I flex it way back.Day 6. Worked at desk all night - crashed - woke up 1:30pm and realized was walking with very little pain. I can thumb press on my right heel and there is only a tiny sharp point which isn't that painful and is very small and very tolerable. Tried walking barefoot - not bad. I am no longer walker bait. My purchased heel inserts and new Wob E bottle haven't arrived yet and I may not need the heel inserts because the heel pain is not bad. Not sending them back though after they arrive - just in case this heel pain comes back.Day 7. Still a painful tiny spot on my heel. I cannot go barefoot because it hurts to walk on hard tile floors but with shoes/sandals - feet feel fine.Day 8. My heel inserts arrived. I used the gel ones inside my shoe and my heel does feel cushioned .When I press my thuumb to the bottom of my foot heel, there is zero pain now BUT when I walk barefoot on hard tile I can feel that sharp digging. Also, if I press the bottom of my heel against my chair's foot, that sharp digging pain is still there but a lot less painfulI never took Wob E every day - but I am now. I will cut down the number of tablets after I am assured this heel issue is gone for good. At least I am not walker bait any longer.Works fast I love this product, gives me so much energyI live far away from my parents and send many gifts in a longing heart, and my mom and dad like this the most! In particular, my mom likes that the pain disappeared a lot after taking this because she had a pain in her finger bone. And so it makes me happyAfter about a month I feel like a new air cushion was installed in between my joints. Sounds silly but so is that it’s the best my lower back and SI joints have felt in years. Quality of life has gone up :)Very impressed with this product.I had a pain in my knee for a while. After taking it for a month, I have no pain anymore. It’s working...that's working for me. Other elements are fish oil, stretching, acupuncture when needed, diet. If you don't want to live a life on steroids, pain killers, etc....My mom has severe degenerative arthritis and is on the list for two knee replacements. In the meantime, she takes 12 of these a day, but she swears by them. She has not slowed down at all, is on her feet running around all day (in her 70's). During her course of taking Wobenzym, she has run out twice - within 1 to 2 days she noticed the inflammation return quickly. I haven't tried this product, but I know my mom, and I believe her if she says this really works.Whoa this stuff is for real!!! Read all the previous reviews cause they are true. Started to relieve the pain right away; by third day all pain in my shoulder was gone. Was doing physio on it every week at $250.00 a session. This is a lot cheaper. Also my urine flow has greatly increased due to what o believe to be the eradication of small tumors in the prostate which most middle aged men will acquire at some point in their lives. Read the second review listed by a woman on Amazon.com site. She extensively lists what this product does in the body at the cellular level. Apparently it's been widely used in Europe for many years. I'm telling everybody I know about.Started using product on June 17/2019 and low and behold within one week noticed knee arthritis pain stated to subside daily and still decreasing, this product has helped tremendously thanks wobenzyme you really helped me with knee painThis works for me by helping me eliminate metabolic waste, it helps me keep my digestive and eliminative system functioning perfectly! I take 2 tablet just before be with a sip of lemon water. That's all I need and some nights I don't take it. It depends on my activity or what I ate that day. If I've eaten naturally foods that lower inflammation for example turmeric (curry) or oregano oil or neem or foods naturally enzymes, papaya, pinapple for example I listen to my body, think logically and sensibly to self-respectfully decide.DO NOT WASTE YOUR MONEY !!!! I took about a month already , 1/3 of bottle, the pain didn’t go away at all !!!! And their Customer Service is Horrible and Terrible !!! They will never reply you or return you any money at all.